Image Analysis of Xerosis and AD Following Prebiotic Skincare Regimen in Ethnically Diverse Patients

This study explores differences in the epidemiology, clinical presentation, and disease course of atopic dermatitis (AD) in patients with Skin of Color (SOC) compared to their white counterparts. The effectiveness of a new imaging device (SkinCam®) was assessed in measuring skin texture changes in diverse AD and xerosis patients following a 10-week prebiotic skincare regimen. A total of 39 participants, aged 3 to 76 years, with Fitzpatrick skin types I to VI and presenting with mild AD and moderate to severe xerosis, were enrolled. The study followed a two-phase skincare routine: a prebiotic cleanser for 2 weeks, followed by the addition of a prebiotic moisturizer for 8 more weeks. Skin texture was monitored using SkinCam® at baseline, week 2, and week 10. The results showed significant improvement in both skin texture irregularity and color patterns over time in both AD (n=12) and xerosis (n=24) patients. Notably, SOC patients (n=18, Fitzpatrick IV-VI) exhibited more pronounced improvement. Furthermore, SkinCam® imaging results aligned with clinical assessments, demonstrating significant skin texture enhancement across all participants by week 10. In conclusion, the SkinCam® device effectively tracks skin texture changes over time in both AD and xerosis patients, including those with light and dark skin.

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Elevate-Derm Alliance Editorial Committee