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Top Clinical Insights: Gut Instincts: Skin Signs of Inflammatory Bowel Disease

  • 20-50% of patients with inflammatory bowel disease will have a cutaneous manifestation.

  • Cutaneous manifestations of inflammatory bowel disease fall under one of four categories: nutritional deficiency, associated conditions, Crohn's-specific and/or treatment-related.

  • Erythema nodosum is the number one associated condition seen in cutaneous manifestations of inflammatory bowel disease.

  • If a patient has neutrophilic dermatosis, keep inflammatory bowel disease in mind.

  • One-third of patients with epidermolysis bullosa acquisita will have inflammatory bowel disease, so they need a GI workup.